Paper on reverse transcription of modified mRNA: Substack I wrote that was referenced in Sonia Elijah interview

Re-post from my other newsletter PLUS the whole interview!

Please head to this latest interview with Sonia Elijah.

"The Many Lies We Were Told..." My Explosive Interview with Dr Jessica Rose

I started to write this article yesterday but not one, but two papers of great interest to me have been published recently and require dissection and dissemination. They are entitled: “MSH3 Homology and Potential Recombination Link to SARS-CoV-2 Furin Cleavage Site” and “Intracellular Reverse Transcription of Pfizer BioNTech COVID-19 mRNA Vaccine BNT162b2 In Vitro in Human Liver Cell Line”, respectively.

Let me be clear here: These COVID-19 injectable products are perfect bioweapons - either by design or accident. Who cares which. The outcome is the same.

Background for future: MSH3 (MutS Homolog 3) is gene that encodes a protein that is responsible for maintaining the stability of our genomes and suppressing tumor formation. This protein is DNA mismatch repair (MMR) protein which means that it recognizes and repairs bad base (nucleotide) insertions, deletions and mis-incorporations that come about inherently as part of DNA recombination and replication as well as DNA repair. You might have heard me talk about this in some of my presentations in reference to the recently-published paper describing 2 enzymes characterized to be inhibited by the spike protein.

…we found that the spike protein localizes in the nucleus and inhibits DNA damage repair by impeding key DNA repair protein BRCA1 and 53BP1 recruitment to the damage site.

This more recent paper shows the presence of a 19 nucleotide-long sequence (19mer) that in fact, contains the sequence that encodes the furin-cleavage site of the SARS-nCoV-2 spike protein. In other fact, this 19mer has 100% sequence identity (100% query cover and matched identity anti-parallel complementarity 5’-3’) with patented sequences from as early as 2015. (I am checking on the link to MSH3.)¹

For GenBank: HZ246785.1, we find CTACGTGCCCGCCGAGGAG which is the reverse compliment of the 19mer CTCCTCGGCGGGCACGTAG which is found in the spike protein of SARS-nCoV-2.

There’s also this one: GenBank: KH664781.1 (SEQ ID NO 11652): the one in the MSH3 paper. There are 4 other patent sequences from Moderna with that 19mer sequence that I found so far (LZ959695.1; LZ959694.1; KH664781.1; KH664780.1). This was no accident.

Most disturbing, however, is that HZ246785.1 was patented 7 years ago by MODERNA THERAPEUTICS (2015) and more recently by ModernaTX Inc (2017/2018). Other patents for this same 19mer were filed by CAMBIA (2015) and CureVac AG (2021). A shorter version with 89% query and 100% matched identity were found in patents filed by Monsanto Technology LLC (2016) and Metanomics GmbH (2015). Just noting some familiar names here. Not making any claims.

Question: Do I need to ask?

Perhaps even more disturbing from a biological point of view, is something that many of us have hypothesized to be possible, has now been proven to be the case. Another new paper (link above) confirms that the Pfizer mRNA incorporates into human DNA. IN AS LITTLE AS 6 HOURS.

We detected high levels of BNT162b2 in Huh7 cells and changes in gene expression of long interspersed nuclear element-1 (LINE-1), which is an endogenous reverse transcriptase.

Huh is right.

Huh cells are ‘immortal’ liver tumor cells and grow ad-infinitum if you give them love. They are good for using in assays that involve viral propagation. LINE-1 is a retrotransposon that we carry endogenously and comprises ~17% of our genome! LINE-1 retrotransposons are necessarily active during embryogenesis are aberrantly active in tumorigenesis.

BNT162b2 mRNA is reverse transcribed intracellularly into DNA as fast as 6 h after BNT162b2 exposure. A possible mechanism for reverse transcription is through endogenous reverse transcriptase LINE-1, and the nucleus protein distribution of LINE-1 is elevated by BNT162b2.² ³ ⁴ ⁵

As can be seen in the following figure extracted from the paper (Figure 3), they found significantly increased LINE-1 expression (V3 = 2.0 µg/mL BNT162b2) compared to control and decreased LINE-1 expression (V1 and V2 = lower BNT162b2 concentrations) at all time points measured.

Line-1 gene expression is increased after 2 days.

LINE-1 retrotransposons are also involved during early embryonic development. Since LINE-1 expression levels are significantly increased then what effect is this over-expression having on embryogenesis?

We found that too much or too little LINE-1 expression caused development to come to a halt. This means that the precise timing and level of retrotransposon expression is critical for the development of the embryo.”

I need a walk. This article will be updated.

And yes, integration into human DNA has been shown in vitro.⁶

Update: Some VAERS plots.

1. Ambati B. et al, MSH3 Homology and Potential Recombination Link to SARS-CoV-2 Furin Cleavage Site. Front.Virol., 21 February 2022 | https://doi.org/10.3389/fviro.2022.834808

2. Coffin, J.M.; Fan, H. The Discovery of Reverse Transcriptase. Annu. Rev. Virol. 2016, 3, 29–51.

3. Kazazian, H.H., Jr.; Moran, J.V. Mobile DNA in Health and Disease. N. Engl. J. Med. 2017, 377, 361–370.

4. Lander, E.S.; Linton, L.M.; Birren, B.; Nusbaum, C.; Zody, M.C.; Baldwin, J.; Devon, K.; Dewar, K.; Doyle, M.; FitzHugh, W.; et al. Initial sequencing and analysis of the human genome. Nature 2001, 409, 860–921.

5. Aldén M, Olofsson Falla F, Yang D, Barghouth M, Luan C, Rasmussen M, De Marinis Y. Intracellular Reverse Transcription of Pfizer BioNTech COVID-19 mRNA Vaccine BNT162b2 In Vitro in Human Liver Cell Line. Current Issues in Molecular Biology. 2022; 44(3):1115-1126. https://doi.org/10.3390/cimb44030073.

6. Zhang, L.; Richards, A.; Barrasa, M.I.; Hughes, S.H.; Young, R.A.; Jaenisch, R. Reverse-transcribed SARS-CoV-2 RNA can integrate into the genome of cultured human cells and can be expressed in patient-derived tissues. Proc. Natl. Acad. Sci. USA 2021, 118, e2105968118.